منابع مشابه
Studies on the Rôle of the Spleen in Experimental Poliomyelitis
1. No difference in susceptibility to infection between splenectomized and non-splenectomized monkeys was observed when virus was injected intravenously in large amounts. 2. In a small series of animals, the results suggested that splenectomy decreased resistance to amounts of virus subinfective for non-splenectomized monkeys. 3. Splenectomy subsequent to intravenous or intrasplenic inoculation...
متن کاملStudies in Rodent Poliomyelitis
1. The murine virus may be grown in embryonic mouse brain-serum ultrafiltrate cultures. The virus fails to grow in embryonic chick tissue cultures or in fertilized egg preparations. 2. Some relationship can be demonstrated between the amount of nervous tissue and the infectivity of the culture. 3. Optimum titers of virus potency (10(-6)) can be obtained by adjusting the pH of the growing cultur...
متن کاملStudies in Rodent Poliomyelitis
A description has been given of the lesions produced in mice and guinea pigs by inoculation of the Jungeblut-Sanders virus. The histopathological findings, although in themselves not conclusive, would tend to support the opinion that Jungeblut and Sanders have transmitted the SK poliomyelitis virus to mouse and guinea pig. In mice the virus apparently retains its affinity for the anterior horns...
متن کاملCutaneous Infectivity in Experimental Poliomyelitis
1. Bilateral olfactory neurectomy did not prevent experimental poliomyelitis on intravenous or intracutaneous inoculation. 2. Various operative procedures increased the susceptibility of monkeys to infection with experimental poliomyelitis.
متن کاملIntraspinous Infection in Experimental Poliomyelitis
By intraspinous injections of specimens of poliomyelitic virus of suitable virulence infection can be caused regularly in Macacus rhesus monkeys. The virus passes from the subarachnoid spaces into the nervous tissues in which it multiplies, and into the blood. The constant involvement of the pia-arachnoid membranes in poliomyelitis, even when no paralysis occurs, and the fact that infection can...
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ژورنال
عنوان ژورنال: Journal of the American Medical Association
سال: 1914
ISSN: 0002-9955
DOI: 10.1001/jama.1914.02560260027008